Molecular Biologists (PhD/Masters)

We are a startup company based in Boston developing next-generation sequencing technologies for clinical diagnostics. We seek Postdoctoral, PhD, and Masters level molecular biologists with experience in molecular genetics, virology, genomics (viral, bacterial, and/or fungal), or nucleic acid biology for development of next-generation clinical assays.

We are looking for an experienced molecular biologist to work in a small team to develop new sequencing-based assays. To fill this role, you need:

• a track record of scientific contributions and publications in a wet-lab using molecular biology tools such as qPCR, sequencing, ligation, cloning, etc
• experience in protocol development or debugging
• an interest in potential applications of sequencing in a variety of fields. We're using our core technology in diverse areas and we need scientists able to quickly learn about new areas applications.
• to be able to work in a small team where you may be asked to fill different roles as our requirements and our clients' requirements change and as projects progress through planning, experimental design, experimental validation, and rollout to collaborators and beta testers.

Ideal candidates will also have experience with:

• computational or statistical analysis of biological data, e.g. R, Matlab, Perl, Python, etc.
• An understanding of genome comparison, phylogenetic analysis, and variant detection would also be useful.
• next-generation sequencing
• laboratory automation or robotics
• GMP laboratory procedures

Senior Scientist

We are a startup company based in Boston developing next-generation sequencing technologies for clinical diagnostics. We seek a senior scientist with experience in one of molecular genetics, virology, genomics (viral, bacterial, and/or fungal), or nucleic acid biology for development of next-generation clinical assays.

You will lead a small team to develop new sequencing-based assays. You will have:

• a track record of scientific contributions and publications in a wet-lab using molecular biology tools such as qPCR, sequencing, ligation, cloning, etc
• expertise in protocol development or debugging
• excitement for developing and applying new technologies. We're using our core technology in diverse areas and we need scientists able to quickly learn about new areas applications
• experience communicating with clients developing project requirements though to beta testing and deployment
• knowledge of GMP and CLIA regulatory requirements

Ideal candidates will also have experience with:

• an understanding of genome comparison, phylogenetic analysis, and variant detection, using R, MATLAB, Perl, Python or other, etc
• next-generation sequencing
• laboratory automation or robotics
• assay deployment

Computational Biologist

Pathogenica is a startup company based in Boston developing next generation sequencing technologies for clinical infectious disease diagnostics. Our core wet-lab technology lets us select small bits of DNA from a sample and sequence them quickly. The computation challenge is to figure out the most informative regions to sequence, determine which of those regions will capture efficiently, and then analyze a potentially noisy sequencing dataset to determine which bacteria, viruses, or fungi were present in a sample and what drug resistance mutations those pathogens carry. Our R&D work uses classical algorithms (DP) and machine learning techniques on DNA sequence analysis and assay design problems. We're also working on analysis software for client sites and for multi-site data aggregation (think lots of systems engineering with a topping of FDA approval).

To fill this role, you need excellent software engineerings skills (primarily in a Unix/Linux environment using Java, Perl, R, and git) and a strong background in algorithms, machine learning, and computational biology. Experience with next generation sequencing data, genome assembly and annotation, phylogenetics, laboratory automation and information systems, or healthcare information systems would be ideal. We're interested in candidates of all educational backgrounds but are looking for substantial and relevant experience in either academia or industry.

Please send

• A copy of your resume or CV
• A short description (1-2 paragraphs) of a project you've worked on that best demonstrates your skills.
• A cover letter including salary history